Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Recurrent brief depression revisited.

Lukas Pezawas1, Jules Angst, Siegfried Kasper

  • 1Department of General Psychiatry, Medical University of Vienna, Vienna, Austria. lukaspezawas@mail.nih.gov

International Review of Psychiatry (Abingdon, England)
|October 1, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Real-world effectiveness and safety of intranasal esketamine for treatment-resistant depression: data from the enTRD registry.

European psychiatry : the journal of the Association of European Psychiatrists·2026
Same author

[Digital health applications for depressive disorders in Germany : A narrative review of the evidence and integration into treatment].

Der Nervenarzt·2025
Same author

Hypomania-Checklist-33: risk stratification and factor structure in a mixed psychiatric adolescent sample.

International journal of bipolar disorders·2024
Same author

Outcomes of electroconvulsive therapy in patients with depressive symptoms with versus without comorbid personality disorders/traits: A systematic review and meta-analysis.

Acta psychiatrica Scandinavica·2023
Same author

The role of affective temperaments in bipolar disorder: The solid role of the cyclothymic, the contentious role of the hyperthymic, and the neglected role of the irritable temperaments.

European psychiatry : the journal of the Association of European Psychiatrists·2023
Same author

Functional connectivity signatures of major depressive disorder: machine learning analysis of two multicenter neuroimaging studies.

Molecular psychiatry·2023
Same journal

Reductions in posttraumatic stress disorder re-experiencing frequency from repetitive transcranial magnetic stimulation combined with Cognitive Processing Therapy.

International review of psychiatry (Abingdon, England)·2026
Same journal

Continuous theta burst stimulation to the frontal pole durably decreases medial frontoamygdala connectivity.

International review of psychiatry (Abingdon, England)·2026
Same journal

What are the arguments for and against recognizing 'terminal' anorexia nervosa? A narrative review.

International review of psychiatry (Abingdon, England)·2026
Same journal

Behavioral addictions in adolescents in Latin America: a narrative review of prevalence, mental health comorbidities, and gaps in care.

International review of psychiatry (Abingdon, England)·2026
Same journal

Persistent suicidality: a concept analysis using Rodgers' evolutionary approach.

International review of psychiatry (Abingdon, England)·2026
Same journal

Extending the evidence for Scrambler Therapy to reduce pain in chemotherapy-induced peripheral neuropathy.

International review of psychiatry (Abingdon, England)·2026
See all related articles

Recurrent Brief Depressive Disorder (RBD) is a common mood disorder linked to increased suicide risk. Combined Depression (RBD and MDD) poses a higher suicide attempt risk than Major Depressive Disorder alone.

Area of Science:

  • Psychiatry
  • Mood Disorders
  • Clinical Psychology

Background:

  • Recurrent Brief Depressive Disorder (RBD) is prevalent and associated with significant impairment and suicidal behavior.
  • RBD episodes occur monthly, lasting a few days.
  • Lifetime co-occurrence with Major Depressive Disorder (MDD), termed Combined Depression (CD), elevates suicide attempt risk beyond MDD alone.

Purpose of the Study:

  • To review the diagnostic criteria and clinical challenges in treating Recurrent Brief Depressive Disorder (RBD).
  • To highlight methodological issues in past treatment studies for RBD.
  • To emphasize the need for future research into effective RBD treatments and biological underpinnings.

Main Methods:

  • Review of diagnostic criteria for RBD (ICD-10, DSM-IV).

Related Experiment Videos

  • Analysis of methodological limitations in previous double-blind, placebo-controlled treatment studies.
  • Examination of reported treatment outcomes in limited patient samples.

    • Main Results:

    • Diagnostic criteria for RBD are established but differ methodologically from MDD.
    • Previous treatment studies for RBD have yielded potentially false-negative results due to methodological issues.
    • Despite some reported successes, a definitive treatment algorithm for RBD remains elusive.

    Conclusions:

    • RBD requires distinct study designs for treatment evaluation compared to MDD.
    • Future research must address limitations of prior studies to establish effective RBD treatments.
    • Ongoing studies are expected to provide insights into the biological basis of RBD.