Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Neonatal lupus erythematosus: a case report.

C M Chen1, Y H Hsu

  • 1Department of Pediatrics, Tzu-Chi Buddhist General Hospital, Hualien, Taiwan, Republic of China.

Gaoxiong Yi Xue Ke Xue Za Zhi = the Kaohsiung Journal of Medical Sciences
|May 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Developmental Changes in Pharyngeal Airway in the Male Population From Adolescence to Adulthood.

European journal of paediatric dentistry·2024
Same author

X-linked adrenoleukodystrophy in a child.

QJM : monthly journal of the Association of Physicians·2024
Same author

[Cytopathological features of hyalinizing trabecular tumor of the thyroid].

Zhonghua bing li xue za zhi = Chinese journal of pathology·2022
Same author

[Construction of prediction model combined dual-energy CT quantitative parameters and conventional CT features for assessing the Ki-67 expression levels in invasive breast cancer].

Zhonghua yi xue za zhi·2022
Same author

Efficient solid-state Raman yellow laser at 579.5  nm.

Optics letters·2020
Same author

Roles of nurses and National Nurses Associations in combating COVID-19: Taiwan experience.

International nursing review·2020
Same journal

[Effect of early intervention on the interaction of developmentally delayed infants and their mothers].

Gaoxiong yi xue ke xue za zhi = The Kaohsiung journal of medical sciences·1995
Same journal

[Risk factors related to alcohol use among adolescents of fathers with alcoholism].

Gaoxiong yi xue ke xue za zhi = The Kaohsiung journal of medical sciences·1995
Same journal

A study of different postures on isometric lifting strength in normal college students.

Gaoxiong yi xue ke xue za zhi = The Kaohsiung journal of medical sciences·1995
Same journal

A clinical analysis of necrotizing fasciitis: a review of 54 cases.

Gaoxiong yi xue ke xue za zhi = The Kaohsiung journal of medical sciences·1995
Same journal

Arthroscopic debridement for osteoarthritis of the knee: a seven years follow-up study.

Gaoxiong yi xue ke xue za zhi = The Kaohsiung journal of medical sciences·1995
Same journal

Comparison of serum CA15-3 and CEA in breast cancer.

Gaoxiong yi xue ke xue za zhi = The Kaohsiung journal of medical sciences·1995
See all related articles

Neonatal lupus erythematosus can present with skin lesions and blood count abnormalities in newborns. Early supportive care and sun avoidance led to gradual recovery of symptoms.

Area of Science:

  • Dermatology
  • Immunology
  • Pediatrics

Background:

  • Neonatal lupus erythematosus (NLE) is a condition affecting newborns, linked to maternal autoantibodies.
  • It can manifest as congenital heart block or cutaneous lupus erythematosus.
  • Maternal autoantibodies, specifically anti-Ro/SSA and anti-La/SSB, are key diagnostic markers.

Observation:

  • A female infant presented with erythematous maculopapules at birth, along with leukopenia and thrombocytopenia.
  • The mother was clinically asymptomatic but tested positive for antinuclear antibodies, anti-Ro/SSA, and anti-La/SSB antibodies.
  • Skin lesions evolved into annular, erythematous patches, with biopsy confirming dermal edema and immune complex deposition.

Findings:

  • The infant exhibited characteristic cutaneous lesions and hematologic abnormalities (leukopenia, thrombocytopenia).

Related Experiment Videos

  • Positive maternal and infant autoantibodies (ANA, anti-Ro/SSA, anti-La/SSB) confirmed NLE.
  • Skin biopsy revealed inflammation and immune complex deposition in the epidermis.

    • Implications:

    • This case highlights the presentation of NLE with cutaneous manifestations and hematologic issues.
    • Supportive treatment and sun avoidance facilitated symptom resolution.
    • The study underscores the importance of maternal autoantibody screening in suspected NLE cases.