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Genetic susceptibility testing from a stress and coping perspective.

Holly C Gooding1, Kurt Organista, Jeffrey Burack

  • 1Division of Health and Medical Sciences, School of Public Health, University of California, 570 University Hall, Berkeley, CA 94720-1190, USA. holly.godding@ucsf.edu

Social Science & Medicine (1982)
|October 4, 2005
PubMed
Summary

Understanding genetic testing for adult-onset diseases is illuminated by health behavior and stress/coping theories. These models help explain decisions for genetic testing, aiding in managing health risks and uncertainty.

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Area of Science:

  • Health Psychology
  • Genetics
  • Behavioral Science

Background:

  • Genetic testing for adult-onset diseases presents complex psychological challenges.
  • Understanding the decision-making process for genetic testing is crucial.

Purpose of the Study:

  • To review four major theories of health behavior and stress/coping.
  • To assess their utility in explaining genetic testing uptake and outcomes for adult-onset diseases.

Main Methods:

  • Review of the Health Belief Model, Theory of Planned Behavior (TPB), Common Sense Model of Self-regulation (CSM), and Transactional Model of Stress and Coping (TMSC).
  • Examination of literature linking these theories to genetic testing for Huntington's disease, Alzheimer's disease, hereditary breast/ovarian cancer, and hereditary colorectal cancer.

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Main Results:

  • Genetic testing decisions can be viewed as a coping mechanism for managing risks associated with adult-onset diseases.
  • Theories focusing on stress and coping effectively address cognitive and affective concerns related to genetic risk.

Conclusions:

  • Theories of stress and coping offer a valuable framework for studying genetic testing decisions.
  • Genetic testing can potentially reduce uncertainty and enhance perceived control over disease risk.