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Ventricular volume and length in hypertensive diastolic heart failure

Mathew S Maurer1, Lyna El Khoury Rumbarger, Donald L King

  • 1Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA. msm10@columbia.edu

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
|October 4, 2005
PubMed

Insights

Patients with hypertensive diastolic heart failure show increased left ventricular volumes and stroke volume, challenging previous assumptions. This suggests a volume overload pattern not detected by standard 2D echocardiography.

Area of Science:

  • Cardiology
  • Cardiovascular Imaging
  • Heart Failure Research

Background:

  • Diastolic heart failure traditionally assumes normal or small ventricles with impaired filling.
  • This study investigates hypertensive diastolic heart failure, questioning the typical ventricular size assumption.

Purpose of the Study:

  • To test the hypothesis that hypertensive diastolic heart failure involves increased left ventricular volumes.
  • To compare left ventricular volumes in patients with hypertensive diastolic heart failure against matched controls.

Main Methods:

  • Utilized 2D and 3D echocardiography to obtain left ventricular chordal dimensions and volumes.
  • Compared data from 96 control subjects and 28 patients with hypertensive diastolic heart failure.
  • Adjusted comparisons for age, sex, and body size.

Main Results:

  • 3D echocardiography revealed significantly larger left ventricular volumes in the heart failure group (P < .05).
  • These volume increases persisted after matching for age, sex, and body size.
  • Increased stroke volume and ventricular centerline length were observed in heart failure patients.

Conclusions:

  • Hypertensive diastolic heart failure patients exhibit significantly increased left ventricular and stroke volumes, indicative of volume overload.
  • Standard 2D echocardiography measurements of ventricular chordal dimensions did not detect this enlargement.
  • Preferential increase in ventricular length appears characteristic of this condition.
Abstract

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