Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The light-addressable potentiometric sensor for multi-ion sensing and imaging.

T Yoshinobu1, H Iwasaki, Y Ui

  • 1The Institute of Scientific and Industrial Research, Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka 567-0047, Japan. nov@ecei.tohoku.ac.jp

Methods (San Diego, Calif.)
|October 4, 2005
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Supernumerary ring chromosomes and nuclear blebs in some low-grade malignant soft tissue tumours: atypical lipomatous tumours and dermatofibrosarcoma protuberans.

Virchows Archiv : an international journal of pathology·1998
Same author

Abortive recombination in Escherichia coli ruv mutants blocks chromosome partitioning.

Genes to cells : devoted to molecular & cellular mechanisms·1998
Same author

Reirradiation therapy for brain metastases from small cell lung cancer.

Radiation medicine·1998
Same author

Remission induction by granulocyte colony-stimulating factor in hypoplastic acute myelogenous leukemia complicated by infection. A case report and review of the literature.

Acta haematologica·1998
Same author

[The efficacy of low-dose propofol for intrathecal morphine-induced pruritus].

Masui. The Japanese journal of anesthesiology·1998
Same author

[Preventive effect of fluid warmer system on hypothermia induced by rapid intravenous infusion].

Masui. The Japanese journal of anesthesiology·1998

Light-addressable potentiometric sensors (LAPS) enable multi-analyte detection on a single chip by using light to access multiple sensing points. This technology is applied to multi-ion sensing and potentiometric imaging in microfluidic channels.

Area of Science:

  • Semiconductor device physics
  • Chemical sensing technology
  • Analytical chemistry

Background:

  • Light-addressable potentiometric sensors (LAPS) are semiconductor devices utilizing an electrolyte-insulator-semiconductor structure.
  • LAPS offer the capability for spatially resolved measurements through individually addressable sensing points on a single chip.
  • Modification of these sensing points allows for the detection of multiple analytes simultaneously.

Purpose of the Study:

  • To describe the instrumentation and application of LAPS for multi-ion sensing.
  • To demonstrate the potential of LAPS for chemical imaging.
  • To introduce potentiometric imaging of microfluidic channels as a novel LAPS application.

Main Methods:

  • Fabrication of LAPS with an electrolyte-insulator-semiconductor structure.

Related Experiment Videos

  • Individual addressing of multiple sensing points on the LAPS surface using a light beam.
  • Modification of sensing points with different materials for multi-analyte detection.
  • Application of LAPS for potentiometric imaging of microfluidic channels.

    • Main Results:

    • Demonstration of LAPS for simultaneous detection of multiple ions.
    • Successful implementation of potentiometric imaging for analyzing microfluidic systems.
    • Validation of LAPS as a versatile platform for multi-analyte sensing and spatial chemical analysis.

    Conclusions:

    • LAPS technology provides a robust platform for multi-analyte sensing and chemical imaging.
    • The ability to individually address sensing points enhances sensor multiplexing capabilities.
    • Potentiometric imaging of microfluidic channels represents a significant advancement in sensor applications.