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Updated: Aug 15, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Management of atrial fibrillation in the emergency department
Arun V Raghavan1, Wyatt W Decker, Thomas D Meloy
1Department of Emergency Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
Insights
Most patients with acute atrial fibrillation (AF) convert to normal rhythm spontaneously. Evidence-based guidelines help determine treatment, including anticoagulation and cardioversion, for stable patients based on AF onset.
Area of Science:
- Cardiology
- Internal Medicine
Background:
- Atrial fibrillation (AF) is a common cardiac arrhythmia with varied treatment approaches.
- An evidence-based strategy is essential for optimal patient care and disposition.
Purpose of the Study:
- To outline an evidence-based approach for managing acute atrial fibrillation.
- To differentiate management strategies for hemodynamically stable versus unstable patients.
Main Methods:
- Review of current evidence regarding atrial fibrillation management.
- Classification of patients based on hemodynamic stability and onset of AF.
Main Results:
- Approximately 50% of acute AF cases resolve spontaneously without intervention.
- For stable patients, the 48-hour onset window is crucial for deciding on anticoagulation and cardioversion.
- Unstable patients require immediate cardioversion regardless of AF duration.
Conclusions:
- An evidence-based approach optimizes acute atrial fibrillation treatment.
- This approach can prevent unnecessary hospitalizations by guiding appropriate interventions.
Abstract:
Although atrial fibrillation remains the most common cardiac arrhythmia, the treatment and disposition remain varied. An accept-able standard of practice requires an evidence-based approach. This approach has revealed that half of the patients who present with acute atrial fibrillation will convert to sinus rhythm without intervention. In the hemodynamically stable subset, ascertaining the on-set of atrial fibrillation within 48 hours is critical because this period dictates when and if anticoagulation should be instituted and if and where electrical or chemical cardioversion needs be performed. The hemodynamically unstable patient, however, requires emergent cardioversion, irrespective of the chronicity of atrial fibrillation. An evidence-based approach may serve to optimize treatment and obviate the need for unnecessary hospital admissions.
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