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Updated: Aug 15, 2026

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
08:35

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Published on: May 26, 2022

[Ca antagonist in the guidelines for the management of hypertension (JSH 2004)]

Satoshi Umemura1

  • 1Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine.

Clinical Calcium
|October 4, 2005
PubMed

Insights

Calcium channel blockers are Japan's top hypertension drugs, offering significant blood pressure reduction with few side effects. They are recommended for various conditions and widely used in combination therapy for sustained 24-hour control.

Area of Science:

  • Cardiology
  • Pharmacology

Context:

  • Calcium channel blockers are the most frequently prescribed antihypertensive medications in Japan.
  • Current hypertension management guidelines (JSH 2004) support their use.

Purpose:

  • To summarize the role and indications of calcium channel blockers in hypertension management in Japan.

Summary:

  • Calcium channel blockers effectively lower blood pressure with a favorable safety profile.
  • They are indicated for patients with stroke, angina, left ventricular hypertrophy, diabetes, and the elderly.
  • These agents are also preferred for combination therapy, providing 24-hour blood pressure control.

Impact:

  • Calcium channel blockers are a cornerstone of hypertension treatment in Japan.
  • Their broad applicability and efficacy support their widespread clinical use.

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