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Coronary surgery in dialysis-dependent patients with end stage renal failure

S M Tugtekin1, K Alexiou, Ch Georgi

  • 1Dept. of Cardiac Surgery, Heart Center Dresden University Hospital, Fetscherstr. 76, 01307, Dresden, Germany. M.Weber@herzzentrum-dresden.com

Zeitschrift Fur Kardiologie
|October 4, 2005
PubMed

Insights

Coronary artery bypass grafting (CABG) in dialysis-dependent end-stage renal failure (ESRF) patients shows good results. This high-risk procedure offers comparable morbidity to patients with normal kidney function.

Area of Science:

  • Cardiology
  • Nephrology
  • Cardiac Surgery

Background:

  • Increasing prevalence of coronary artery disease (CAD) in end-stage renal failure (ESRF) patients requiring dialysis.
  • Coronary artery bypass grafting (CABG) is standard but carries high risks in this population.

Purpose of the Study:

  • To evaluate the clinical outcomes of isolated CABG in dialysis-dependent ESRF patients.
  • To compare morbidity and mortality of CABG in ESRF patients versus those with normal renal function.

Main Methods:

  • Retrospective analysis of 40 dialysis-dependent ESRF patients undergoing isolated CABG with extracorporeal circulation.
  • Comparison with a control group of 51 patients with normal renal function undergoing isolated CABG.

Main Results:

  • Hospital mortality was 2.5% in the ESRF group versus 0% in the control group.
  • Comparable perioperative morbidity between the ESRF and control groups.
  • Mean follow-up of 34 months in the ESRF group with 8 deaths.

Conclusions:

  • CABG can be performed with good clinical results in dialysis-dependent ESRF patients.
  • Morbidity is comparable to patients with normal renal function, suggesting CABG is a viable option.

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