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Updated: Aug 6, 2026

A Pacing-Controlled Procedure for the Assessment of Heart Rate-Dependent Diastolic Functions in Murine Heart Failure Models
Published on: July 21, 2023
Heart failure and health related quality of life
Rui Coelho1, Sónia Ramos, Joana Prata
1Department of Psychiatry, Hospital de S. João, Porto Medical School, Porto, Portugal. rmnscoelho@mail.telepac.pt
Insights
Quality of life is a key goal in cardiology care and clinical trials for congestive heart failure (CHF). Further research is needed to identify patient-centered quality of life measures that impact prognosis.
Area of Science:
- Cardiology
- Preventive Medicine
- Clinical Trials
Background:
- Quality of life (QoL) is a critical consideration in both preventive and therapeutic cardiology.
- It serves as a vital outcome measure in clinical trials for congestive heart failure (CHF).
- Physicians also consider QoL in individual patient treatment decisions.
Purpose of the Study:
- To review concepts of quality of life in cardiology.
- To explore methods for measuring quality of life.
- To discuss clinically significant changes in quality of life and their impact on prognosis.
Main Methods:
- Literature review of quality of life concepts.
- Exploration of measurement methodologies.
- Discussion of prognostic implications of QoL changes.
Main Results:
- Quality of life is integral to patient-centered cardiovascular care.
- Current measurement approaches and their clinical significance are examined.
- The relationship between QoL and patient prognosis is highlighted.
Conclusions:
- There is a need for enhanced research focusing on carefully selected QoL measures.
- Measures should prioritize patient importance and align with research hypotheses.
- Improved QoL assessment can refine therapeutic decisions and trial outcomes in cardiology.
Abstract:
Quality of life is a major goal in the context of preventive and therapeutic cardiology. It is important, both as an outcome measure in clinical trials of congestive heart failure (CHF) and as a consideration in individual physicians' therapeutic decisions. In this article, quality of life concepts are reviewed, methods of measurement are explored and clinically significant changes on prognosis are discussed. There is a need for more research which is based on carefully selected measures of quality of life chosen as being of particular importance to patients and to the hypotheses being tested.
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