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[Association between serum uric acid and triglyceride in a Chinese community]
Lan-jiang Zhao1, Dong Zhao, Jing Liu
1Department of Epidemiology, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Capital University Affiliationg Beijing Anzhen Hospital, Beijing 100029, China.
Objective:
To Study the association between the level of serum uric acid and triglyceride in a Chinese population.
Methods:
In 1999, a cross-sectional study was carried out in a natural population of Beijing, using stratified-random sampling method. Serum uric acid and triglyceride were measured in 1239 subjects.
Results:
The prevalence of hypertriglyceridemia significantly increased with increased level of serum uric acid among both the men and women. After adjusting BMI, HOMA index and alcohol consumption level with stratified methods, the incidence of hypertriglyceridemia increased with increasing level of basal serum uric acid in different levels of BMI, HOMA index and alcohol consumption. After adjusting gender, age, BMI, HOMA index, total cholesterol, smoking and alcohol consumption, the results of multivariate logistic regression analyses indicated that the odds ratio for hypertriglyceridemia as compared with the lowest quartile of serum uric acid was 1.26 (P = 0.28) for the second quartile, 1.88 (P = 0.002) for the third quartile, and 3.36 (P < 0.001) for the highest quartile.
Conclusions:
Serum uric acid level was strongly associated with triglyceride independent of age, genders, smoking, alcohol consumption, obesity and insulin resistance.