Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pupillary escape.

T A Cox1

  • 1Department of Ophthalmology, University of Utah Medical School, Salt Lake City.

Neurology
|July 1, 1992
PubMed
Summary
This summary is machine-generated.

Pupillary escape testing is not a reliable method for detecting optic nerve and retinal diseases. This study found it ineffective, even when relative afferent pupillary defects were present.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Orbital socket contracture: a complication of inflammatory orbital disease in patients with Wegener's granulomatosis.

The British journal of ophthalmology·2005
Same author

Choroidal neovascular membrane inhibition in a laser treated rat model with intraocular sustained release triamcinolone acetonide microimplants.

The British journal of ophthalmology·2003
Same author

Safety and pharmacokinetics of intravitreal 2-methoxyestradiol implants in normal rabbit and pharmacodynamics in a rat model of choroidal neovascularization.

Experimental eye research·2002
Same author

Intracameral anesthesia: a report by the American Academy of Ophthalmology.

Ophthalmology·2001
Same author

Pars plana vitrectomy, subretinal injection of tissue plasminogen activator, and fluid-gas exchange for displacement of thick submacular hemorrhage in age-related macular degeneration.

American journal of ophthalmology·2001
Same author

Does levodopa improve visual function in NAION?

Ophthalmology·2000
Same journal

Teaching Video NeuroImage: Tardive Blepharoclonus.

Neurology·2026
Same journal

Teaching NeuroImage: Latent Axonal Degeneration in Patient With Anterior Circulation Stroke.

Neurology·2026
Same journal

Incidental DWI-Positive Lesions in 2 Cohorts of CAA and CADASIL: Prevalence, Distribution, and Associations With Clinical Variables.

Neurology·2026
Same journal

Alpha-Synuclein Seed Amplification Assay in CSF, Skin, and Submandibular Gland From Incidental Lewy Body Disease and Parkinson Disease.

Neurology·2026
Same journal

Digital Semiology.

Neurology·2026
Same journal

Early Cerebral Edema Subtypes and Functional Outcome in Patients With Cerebral Venous Thrombosis: Insights From the CLOT-VENUS Registry.

Neurology·2026
See all related articles

Area of Science:

  • Ophthalmology
  • Neuroscience
  • Optometry

Background:

  • Pupillary abnormalities can indicate optic nerve and retinal disease.
  • Pupillary escape is a phenomenon that has been investigated as a potential diagnostic indicator.

Purpose of the Study:

  • To evaluate the clinical effectiveness of pupillary escape testing in diagnosing optic nerve and retinal diseases.

Main Methods:

  • A pupillographic study was conducted.
  • The study included 14 patients with suspected optic nerve or retinal disease and 39 healthy control subjects.

Main Results:

  • Only one patient exhibited abnormal pupillary escape.
  • Thirteen patients had relative afferent pupillary defects, indicating underlying visual pathway damage.

Related Experiment Videos

  • A significant discrepancy was observed between the presence of relative afferent pupillary defects and abnormal pupillary escape.
  • Conclusions:

    • Pupillary escape testing is not a reliable clinical technique for detecting optic nerve and retinal disease.
    • The findings suggest that other diagnostic methods are more effective for identifying these conditions.