[Sedation with continuously infused propofol in caudal block for elective pediatric surgery]
Related Experiment Video
Updated: Oct 21, 2026

Guidelines for Elective Pediatric Fiberoptic Intubation
Published on: January 17, 2011
G Bifarini1, A Spaccatini, B Ciammitti
1Istituto di Anestesiologia e Rianimazione, Università degli Studi di Perugia.
Insights
This study found that combining caudal block with propofol infusion provides safe and effective anesthesia for pediatric surgery. Patients experienced good sedation, stable vitals, and quick recovery with minimal side effects.
Area of Science:
- Anesthesiology
- Pediatric Surgery
Context:
- Regional analgesia, specifically caudal blocks, is used in pediatric surgery.
- Continuous propofol infusion is an option for maintaining anesthesia.
Purpose:
- To evaluate the safety and efficacy of combining caudal block with continuous propofol infusion in pediatric patients undergoing general surgery.
Summary:
- Twenty-nine pediatric patients (2 months to 6 years) received caudal block combined with a continuous propofol infusion (3 mg/kg/h).
- Hemodynamic parameters (heart rate, arterial pressure, SaO2, respiratory rate) and side effects were monitored during anesthesia and recovery.
- The combination resulted in satisfactory sedation, stable cardiovascular and respiratory function, and rapid recovery.
Impact:
- This combined anesthetic technique appears to be a rational and safe approach for pediatric surgical procedures.
- It offers a potential alternative for achieving adequate anesthesia and analgesia in young children.
Abstract:
Twenty-nine patients aged between 2 months and 6 years, undergoing general surgery under regional analgesia (caudal block) combined with continuous infusion of propofol (3 mg/kg/h), were studied. During anesthesia the heart rate, the arterial pressure, the SaO2 and respiratory rate were recorded; the electrocardiogram was continuously displayed and all side-effects occurring during maintenance and recovery from anesthesia were noted. Satisfactory sedation without significant respiratory and cardiovascular depression and a rapid recovery, was observed. In conclusion, we feel that the use of combined caudal block and continuous infusion of propofol for paediatric surgery is rational.
More Related Videos
07:54Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
08:58Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs
Published on: October 31, 2025
Related Concept Videos
Depolarizing Blockers: Pharmocokinetics
Skeletal Muscle Relaxants: Therapeutic Uses
Local Anesthetics: Clinical Application as Spinal Anesthesia
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Stages of General Anesthesia
Parenteral Anesthetics: Overview