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Skeletal infections in cirrhotics
G Rajesh1, Rajiv Mehta, R Nandakumar
1Department of Gastroenterology, Amrita Institute of Medical Sciences, Amrita Lane, Elamakkara P O, Cochin 682 026, India. gastro@aimshospital.org
Summary
Skeletal infections are rare in cirrhosis patients. This study details two cases of alcoholic liver disease with bone infections: pyogenic discitis and tubercular osteomyelitis, highlighting varied outcomes.
Area of Science:
- Infectious Diseases
- Hepatology
- Orthopedics
Background:
- Skeletal infections are infrequently reported in patients with cirrhosis.
- Alcoholic liver disease is a significant risk factor for various complications.
Observation:
- Two cases of skeletal infections in patients with alcoholic liver disease were observed within one year.
- Case 1: A 46-year-old male presented with pyrexia of unknown origin, diagnosed with pyogenic discitis.
- Case 2: A 42-year-old male presented with a chest wall abscess, diagnosed with tubercular osteomyelitis.
Findings:
- Pyogenic discitis in the first patient resolved with antibiotic therapy and surgical intervention.
- The second patient with tubercular osteomyelitis unfortunately expired despite treatment with non-hepatotoxic anti-tubercular drugs.
Implications:
- These cases underscore the importance of considering skeletal infections in cirrhotic patients, particularly those with alcoholic liver disease.
- The diverse etiologies and outcomes emphasize the need for prompt diagnosis and tailored treatment strategies.
- Further research is warranted to understand the pathophysiology and optimize management of bone infections in this vulnerable population.