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Comparison of five MR sequences for the detection of acute intracranial hemorrhage

Catherine Oppenheim1, Emmanuel Touzé, Danielle Hernalsteen

  • 1Department of Neuroradiology, Sainte-Anne Hospital, Paris V University, France. e.oppenheim@ch-sainte-anne.fr

Cerebrovascular Diseases (Basel, Switzerland)
|October 6, 2005
PubMed
Abstract

Insights

Five magnetic resonance (MR) imaging sequences effectively distinguish acute intracerebral hemorrhage (ICH) in stroke patients. All tested sequences demonstrated high accuracy, aiding in rapid diagnosis and patient management.

Area of Science:

  • Radiology
  • Neurology
  • Medical Imaging

Background:

  • Acute intracerebral hemorrhage (ICH) is a critical complication of stroke.
  • Accurate and timely diagnosis of ICH is essential for appropriate patient management.
  • Magnetic Resonance (MR) imaging plays a crucial role in stroke evaluation.

Purpose of the Study:

  • To assess the diagnostic performance of five different MR imaging sequences.
  • To determine the effectiveness of each sequence in differentiating acute ICH from non-ICH in stroke patients.
  • To compare the value of T1-weighted, T2-weighted gradient echo (GRE), FLAIR, T2-EPI, and DWI sequences.

Main Methods:

  • Retrospective review of MR images from 86 acute stroke patients (43 with ICH, 43 without).
  • Images were acquired within 6 hours of stroke onset.
  • Three independent observers evaluated each of the five MR sequences (T1, T2 GRE, FLAIR, T2-EPI, DWI) for signs of acute ICH.

Main Results:

  • High intraobserver and interobserver agreement (kappa >= 0.95) across all sequences.
  • FLAIR, T2-EPI, and DWI achieved 100% sensitivity and specificity for ICH detection.
  • GRE and T1 sequences also demonstrated high sensitivity and specificity, with minor variations.
  • Misclassifications on one sequence were corrected by others, indicating robustness.

Conclusions:

  • All five evaluated MR sequences are highly sensitive and specific for distinguishing acute ICH in stroke patients.
  • These sequences provide reliable diagnostic information in the early hyperacute phase of stroke.
  • The findings support the utility of these MR sequences in the clinical evaluation of acute stroke.

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