Related Experiment Video
Updated: Aug 15, 2026
Robotic-assisted Bronchoscopy Combined with Multimodal Imaging for Targeted Lung Cryobiopsies
Published on: July 19, 2024
Perioperative analysis of biopsies issued from mediastinoscopy
M Alifano1, M C Charpentier, C Perrotin
1Unité de Chirurgie Thoracique, Université Paris V, Hôtel-Dieu, 1, Place du Parvis Nôtre-Dame, 75004 Paris, France.
Background:
The objective of this study was to evaluate frozen sections of samples obtained at mediastinoscopy for their clinical usefulness.
Methods:
This study retrospectively reviewed the records of all patients who underwent mediastinoscopy with perioperative frozen sections in a 1-year period.
Results:
A total of 123 consecutive patients underwent the procedure. There were no false-positive results. Of the 71 malignant proliferations, 67 were diagnosed from frozen sections. The technique never failed to establish the absence of mediastinal nodal involvement in patients with suspected or proven lung tumors and enlarged nodes (n = 18) who underwent immediate thoracotomy. Frozen sections allowed recognition (n = 36) or strong suspicion (n = 4) of N2 disease in patients subsequently treated by induction chemotherapy. The technique never failed to establish the nonresectability of lung cancer in patients for whom this condition was suspected perioperatively (clinical stage IIIb; n = 10).
Conclusions:
Mediastinoscopy with frozen sections remains an extremely useful tool for the management of paratracheal or subcarinal mediastinal disease.
