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Interactome-Seq: A Protocol for Domainome Library Construction, Validation and Selection by Phage Display and Next Generation Sequencing
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Inferring protein domain interactions from databases of interacting proteins

Robert Riley1, Christopher Lee, Chiara Sabatti

  • 1Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, CA 90095, USA. riley@mbi.ucla.edu

Genome Biology
|October 7, 2005
PubMed
Summary

Domain Pair Exclusion Analysis (DPEA) infers protein domain interactions from protein interaction data. This method identified 3,005 high-confidence domain interactions, aiding future experimental discoveries.

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