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[Kikuchi-Fujimoto disease].

Alice Reichert¹, T Correia, O Freitas

¹Unidade de Imunohematologia, Hospital de Dona Estefânia, Lisboa.

Acta Medica Portuguesa

|October 7, 2005

Summary

Kikuchi and Fujimoto's disease, a rare lymph node disorder, can affect young adults and children. This case highlights a pediatric patient who successfully responded to steroid treatment for this condition.

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Area of Science:

Immunology
Pathology
Pediatrics

Background:

Kikuchi and Fujimoto's disease (KFD), or histiocytic necrotizing lymphadenopathy, is a rare, benign lymph node disorder primarily affecting young adults.
The exact etiology of KFD remains unknown, with autoimmune mechanisms and viral associations suggested.
KFD presents with symptoms including persistent fever, lymphadenopathy, and weight loss.

Observation:

This report details a pediatric case of KFD in a 14-year-old girl.
The patient presented with persistent fever, significant cervical lymphadenopathy, and unexplained weight loss.
Histological examination of the cervical lymph node confirmed the diagnosis of KFD.

Findings:

The pediatric patient diagnosed with Kikuchi and Fujimoto's disease exhibited a significant positive response to corticosteroid therapy.
Histological analysis of lymph node biopsy was crucial for accurate diagnosis.

Implications:

This case underscores the importance of considering KFD in pediatric patients with unexplained fever and lymphadenopathy.
Steroid therapy appears to be a beneficial treatment option for pediatric cases of Kikuchi and Fujimoto's disease.
Further research into the etiology and optimal management of KFD in pediatric populations is warranted.

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