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Naive CD4+ cells from cord blood can generate competent Th effector cells

Elisabet Cantó1, José L Rodríguez-Sánchez, Sílvia Vidal

  • 1Department of Immunology, Institut Recerca i Hospital Santa Creu i Sant Pau, Barcelona, Spain.

Transplantation
|October 8, 2005
PubMed
Summary

Umbilical cord blood (UCB) T cells are as effective as adult cells in generating Th effector cells. UCB cells show higher IL-10 production, but this is balanced by increased IL-2 and CD25 expression, ensuring robust immune responses.

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