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Updated: Aug 15, 2026

Minimally Invasive Cisterna Magna Injection Model for Leptomeningeal Metastasis Studies in Mice
Published on: May 23, 2025
Neurosurgical interventions for leptomeningeal tumor
Jeffrey P Greenfield1, Mark H Bilsky
1Department of Surgery, Neurosurgery Service, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.
Abstract:
Nonsurgical modalities remain the keystone to treatment and control of leptomeningeal tumor. However, neurosurgical consultation is often required for placement of Ommaya reservoirs and ventriculoperitoneal shunts. In this chapter, the utility of these devices, as well as their common complications will be presented. The aim will be to familiarize non-surgical providers with the indications for and complications associated with these neurosurgical procedures as a component of the adjuvant treatment of leptomeningeal disease.
