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Related Experiment Videos

Pharmacological treatment for premature ejaculation.

Daniel Richardson1, David Goldmeier

  • 1Jane Wadsworth Clinic, Jefferiss Wing, St Mary's Hospital, London W2 1UF, UK. daniel.richardson@st-marys.nhs.uk

International Journal of STD & AIDS
|October 11, 2005
PubMed
Summary

Selective serotonin reuptake inhibitors (SSRIs) effectively treat premature ejaculation, often with local anesthetic cream. This study also found high rates of co-existing prostatitis, erectile dysfunction, and anxiety in patients.

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Area of Science:

  • Urology
  • Sexual Health
  • Pharmacology

Background:

  • Premature ejaculation (PE) is a prevalent male sexual dysfunction.
  • Established treatments include behavioral therapy, tricyclic antidepressants, SSRIs, and local anesthetic creams.
  • Co-existing conditions like prostatitis, erectile dysfunction (ED), and anxiety are frequently observed in men with PE.

Purpose of the Study:

  • To audit the effectiveness of prescribed treatments for PE in a dedicated sexual dysfunction clinic.
  • To investigate the prevalence of co-existing prostatitis/male pelvic pain, ED, phosphodiesterase-5 (PDE5) inhibitor use, and anxiety in patients with PE.
  • To assess the success of SSRIs in managing PE, with or without adjunctive local anesthetic cream.

Main Methods:

  • Retrospective audit of a clinical cohort from a sexual dysfunction clinic.

Related Experiment Videos

  • Analysis of treatment outcomes for premature ejaculation.
  • Assessment of co-morbidities including prostatitis/male pelvic pain, erectile dysfunction, PDE5 inhibitor use, and anxiety.

    • Main Results:

    • Selective serotonin reuptake inhibitors (SSRIs) demonstrated success in treating premature ejaculation.
    • Adjunctive use of local anesthetic cream with SSRIs did not significantly alter treatment success rates.
    • High prevalence of co-existing prostatitis/male pelvic pain, erectile dysfunction, PDE5 inhibitor use, and anxiety was noted.

    Conclusions:

    • SSRIs are an effective pharmacotherapy for premature ejaculation.
    • Co-existing prostatitis/male pelvic pain, erectile dysfunction, and anxiety are common in men presenting with premature ejaculation.
    • Further research may be warranted to explore integrated treatment approaches for these co-existing conditions.