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Murine Full-thickness Skin Transplantation
Published on: January 2, 2017
Improving transplantation programs and patient care
1Saudi Center for Organ Transplantation, Riyadh, Saudi Arabia. famshaheen@yahoo.com
Abstract:
Organ transplantation is the preferred mode of replacement therapy. Currently acceptable 5-year posttransplantation survival rates are 85% for renal grafts, 70% for liver, and 65% for heart. Organ donation, however, remains a significant factor in organ transplantation, as humans are the only possible donors and the numbers of patients on waiting lists remain high. Several factors affect organ transplantation in countries in the Middle East Society for Organ Transplantation (MESOT) region, including inadequate preventive medicine, differing health infrastructures, poor awareness within the medical community and lay public regarding the importance of organ donation and transplantation, a high level of ethnicity, and poor government support of organ transplantation. Moreover, there is lack of team spirit among transplant physicians, a lack of coordination between groups that manage organ procurement and the transplant centers, and a lack of effective health insurance coverage for many persons. Three models of organ donation and transplantation exist in the MESOT region-the Saudi, Iranian, and Pakistani models. Living-organ donation, the most widely practiced form of donation in countries in the MESOT region, includes kidney and partial liver. Cadaveric organ donation has significant potential in the MESOT region. However, numerous obstacles must be overcome in MESOT countries. Resolution of these obstacles will require continuous work on many fronts. Experiences from all sources must be incorporated into new and improved models that can overcome current inadequacies. Solutions will require continued focus within the medical community, steady support from the lay public and religious institutions, as well as governmental assistance.
Insights
Organ donation and transplantation face challenges in the Middle East Society for Organ Transplantation (MESOT) region due to various factors. Overcoming these requires improved awareness, infrastructure, and governmental support for organ transplantation.
Area of Science:
- Medical Science
- Transplantation Medicine
- Public Health
Background:
- Organ transplantation is a vital replacement therapy with established survival rates for renal, liver, and heart grafts.
- Organ donation is a critical bottleneck, with high patient waiting lists and limited donor availability.
- The Middle East Society for Organ Transplantation (MESOT) region faces unique challenges impacting organ transplantation.
Purpose of the Study:
- To identify and analyze the factors affecting organ transplantation in the MESOT region.
- To explore existing organ donation and transplantation models within the MESOT region.
- To propose solutions for improving organ donation and transplantation outcomes in MESOT countries.
Main Methods:
- Review of factors influencing organ transplantation in the MESOT region.
- Analysis of existing organ donation and transplantation models (Saudi, Iranian, Pakistani).
- Identification of obstacles to cadaveric organ donation and living-organ donation practices.
Main Results:
- Key challenges include inadequate preventive medicine, fragmented health infrastructures, and low awareness of organ donation importance.
- Lack of team spirit among physicians, poor coordination in organ procurement, and insufficient health insurance coverage are significant barriers.
- Living-organ donation (kidney, partial liver) is prevalent, while cadaveric donation has untapped potential.
Conclusions:
- Addressing organ transplantation barriers in the MESOT region requires a multi-faceted approach.
- Enhancing organ donation necessitates continuous medical community efforts, public and religious support, and governmental assistance.
- Developing improved models by incorporating diverse experiences is crucial for overcoming current inadequacies in organ transplantation.
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