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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

823
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
823
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

918
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
918
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

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Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
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Acute Kidney Injury I: Introduction01:22

Acute Kidney Injury I: Introduction

1.4K
Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
1.4K
Acute Kidney Injury II: Pathophysiology01:29

Acute Kidney Injury II: Pathophysiology

2.2K
Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
2.2K
Acute Kidney Injury III: Clinical Manifestations01:29

Acute Kidney Injury III: Clinical Manifestations

1.7K
Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
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Related Experiment Video

Updated: Apr 26, 2026

Mouse Kidney Transplantation: Models of Allograft Rejection
16:15

Mouse Kidney Transplantation: Models of Allograft Rejection

Published on: October 11, 2014

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Spontaneous kidney allograft rupture.

H Shahrokh1, H Rasouli, M A Zargar

  • 1Hasheminejad Medical Center, Tehran, Iran. hosseinshahrokh@hotmail.com

Transplantation Proceedings
|October 11, 2005
PubMed
Summary

Spontaneous renal allograft rupture is a serious kidney transplant complication. Graft repair is recommended over nephrectomy for better outcomes.

Area of Science:

  • Nephrology
  • Transplant Surgery
  • Immunology

Background:

  • Spontaneous renal allograft rupture is a rare but severe complication of kidney transplantation.
  • It can lead to graft loss and necessitates urgent surgical intervention.
  • Predisposing factors include acute rejection, acute tubular necrosis, and renal vein thrombosis.

Purpose of the Study:

  • To evaluate the incidence and management outcomes of spontaneous renal allograft rupture.
  • To compare graft nephrectomy with graft repair in treating renal allograft rupture.

Main Methods:

  • Retrospective review of medical records of 1682 living donor kidney transplant recipients from 1986-2003.
  • Analysis of six cases of spontaneous renal allograft rupture.
  • Comparison of outcomes between graft nephrectomy and graft repair.

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Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach
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A Rat Orthotopic Renal Transplantation Model for Renal Allograft Rejection
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A Rat Orthotopic Renal Transplantation Model for Renal Allograft Rejection

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Related Experiment Videos

Last Updated: Apr 26, 2026

Mouse Kidney Transplantation: Models of Allograft Rejection
16:15

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Published on: October 11, 2014

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Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach
09:15

Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach

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A Rat Orthotopic Renal Transplantation Model for Renal Allograft Rejection
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Main Results:

  • Six cases (0.35%) of spontaneous renal allograft rupture were identified, all preceded by acute graft rejection.
  • Three grafts were removed (nephrectomy), while three were repaired.
  • Two out of three repaired grafts had good outcomes.

Conclusions:

  • Graft repair should be considered the primary procedure of choice for spontaneous renal allograft rupture.
  • Successful graft repair can be achieved, offering a viable alternative to nephrectomy.