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Updated: Aug 15, 2026

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
Published on: March 20, 2015
Surface-enhanced Raman scattering on colloidal nanostructures
R F Aroca1, R A Alvarez-Puebla, N Pieczonka
1Materials and Surface Science Group, University of Windsor, Windsor, Ontario, Canada. raroca1@cogeco.ca
Abstract:
Surface-enhanced Raman scattering combines extremely high sensitivity, due to enhanced Raman cross-sections comparable or even better than fluorescence, with the observation of vibrational spectra of adsorbed species, providing one of the most incisive analytical methods for chemical and biochemical detection and analysis. SERS spectra are observed from a molecule-nanostructure enhancing system. This symbiosis molecule-nanostructure is a fertile ground for theoretical developments and a realm of applications from single molecule detection to biomedical diagnostic and techniques for nanostructure characterization.

