Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Is restless legs syndrome underrecognized? Current management.

Pascale Vergne-Salle1, Damien Coyral, Karine Dufauret

  • 1Rheumatology and Therapy department, CHU Dupuytren, 2, av Martin-Luther-King, 87042 Limoges cedex, France. pascale.vergne-salle@chu-limoges.fr

Joint Bone Spine
|October 11, 2005
PubMed
Summary

Restless legs syndrome (RLS) causes uncomfortable leg sensations and an urge to move, often worsening at night. Treatment focuses on the cause for secondary RLS or symptom relief for severe cases.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cervical isthmic spondylolysis.

Joint bone spine·2026
Same author

The longitudinal association between anticholinergic burden and cognitive-functional decline among older adults.

British journal of clinical pharmacology·2026
Same author

Comparison of two strategies of glucocorticoid withdrawal in patients with rheumatoid arthritis in low disease activity (STAR): a randomised, placebo- controlled, double-blind trial.

Annals of the rheumatic diseases·2025
Same author

Non-hematological triggers of VEXAS syndrome: A case report and literature review.

Current research in translational medicine·2024
Same author

Comparison of two strategies of glucocorticoid withdrawal in patients with rheumatoid arthritis in low disease activity (STAR): a randomised, placebo-controlled, double-blind trial.

Annals of the rheumatic diseases·2024
Same author

Systemic Scleroderma Induced by Nivolumab in Malignant Melanoma.

In vivo (Athens, Greece)·2024

Area of Science:

  • Neurology
  • Sleep Medicine

Background:

  • Restless legs syndrome (RLS) is a neurological disorder affecting 10-15% of Caucasians.
  • Characterized by an irresistible urge to move the legs, often accompanied by dysesthesia.
  • Symptoms worsen during inactivity, particularly in the evening and at night, with relief upon movement.

Purpose of the Study:

  • To outline the understanding, diagnosis, and management of Restless Legs Syndrome.
  • To differentiate between idiopathic and secondary RLS.
  • To review current treatment strategies for RLS.

Main Methods:

  • Literature review of RLS pathophysiology, prevalence, and clinical presentation.
  • Analysis of diagnostic criteria, including polysomnography findings (80% show periodic leg movements).

Related Experiment Videos

  • Summary of etiological factors for secondary RLS (e.g., iron deficiency, renal failure, medications).

    • Main Results:

    • Idiopathic RLS often has a familial component.
    • Secondary RLS is linked to various underlying medical conditions and medications.
    • Polysomnography confirms periodic leg movements in most RLS cases.

    Conclusions:

    • Management of secondary RLS involves treating the underlying cause.
    • Symptomatic treatment is crucial for patients with moderate-to-severe RLS impacting quality of life.
    • Pharmacological interventions include dopaminergic agents, weak opioids, benzodiazepines, anticonvulsants, and strong opioids if necessary.