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Updated: Aug 15, 2026

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
Published on: June 28, 2018
Microbiology of acute otitis media with tympanostomy tubes
Peter S Roland1, David A Parry, David W Stroman
1Department of Otolaryngology, UT Southwestern Medical Center, Dallas, TX 75390, USA. peter.roland@utsouthwestern.edu
Objective:
The objective was to determine the types of organisms which cause acute otitis media with a tympanostomy tube and to ascertain their frequency distribution.
Study Design And Setting:
Prospective, randomized, multi-institutional clinical trials. Both private and academic sites were included.
Results:
1309 isolates were recovered from 956 draining ears. Streptococcus pneumonia was recovered from 17%, Staphylococcus aureus from 13%, H flu from 18% and Pseudomonas aeruginosa from 12%. Fungal organisms were recovered from 5% of total isolates and 4% from single isolates.
Conclusions:
AOMT is microbiologically different than AOM with an intact TM. There is no evidence that resistance develops as result of topical treatment.
Significance:
The study demonstrates that AOMT is frequently caused by organisms not susceptible to oral antibiotics approved for children, but which are sensitive to topical ear drops.
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