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Arginine: a clinical perspective.

Hemendra N Basu1, George U Liepa

  • 1Department of Human, Environmental and Consumer Resources, Eastern Michigan University, 210 Roosevelt Hall, Ypsilanti, Michigan 48197, USA.

Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition
|October 11, 2005
PubMed
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Dietary arginine, found in foods and supplements, positively impacts cardiovascular health, immunity, and wound healing. Long-term safety data is limited for specific populations like cancer patients.

Area of Science:

  • Nutrition Science
  • Biochemistry
  • Pharmacology

Background:

  • Dietary arginine is a common nutrient in plant and animal products.
  • Arginine supplements have gained popularity over the last two decades.
  • Arginine influences cardiovascular, immune, and wound healing processes.

Purpose of the Study:

  • To review the known effects of dietary arginine.
  • To explore arginine's interactions with pharmaceutical therapies.
  • To assess the safety profile of arginine supplementation.

Main Methods:

  • Literature review of existing studies on arginine.
  • Analysis of research on arginine's physiological effects.
  • Examination of clinical data on arginine safety and efficacy.

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Main Results:

  • Arginine demonstrates beneficial effects on the cardiovascular system, immune function, and wound healing.
  • Positive interactions between arginine and statin medications have been observed.
  • Arginine is considered safe for short-term use with positive physiological outcomes.

Conclusions:

  • Arginine supplementation shows promise for various health benefits.
  • Further research is needed on the long-term safety of pharmaceutical doses of arginine, especially in patient populations like cancer survivors.