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Probiotics as functional foods.

David C Lin1

  • 1Department of Biochemistry and Pathology, Southern California University of Health Sciences, 16200 E. Amber Valley Drive, P. O. Box 1166, Whittier, California 90609-1166, USA. davidlin@scuhs.edu

Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition
|October 11, 2005
PubMed
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Probiotics, beneficial bacteria found in supplements, offer potential health benefits like improved digestion and immune function. Research indicates they may help manage various gut conditions, though specific mechanisms require further study.

Area of Science:

  • Microbiology
  • Nutrition Science
  • Gastroenterology

Background:

  • Probiotic products are increasingly popular as food supplements in the United States, following widespread use in Japan and Europe.
  • Understanding the biological nature, available products, health claims, and safety of probiotics is crucial for consumers and nutrition professionals.
  • Probiotics are functional foods providing health benefits beyond basic nutrition.

Purpose of the Study:

  • To review the scientific literature on probiotics, focusing on their health benefits, safety, and regulation.
  • To consolidate evidence regarding the effects of probiotics on intestinal microflora, disease prevention, and immune modulation.

Main Methods:

  • Systematic review of scientific papers published in major nutrition journals.

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  • Analysis of abstracts available on the PubMed website concerning probiotics.

    • Main Results:

    • Probiotics, primarily Lactobacillus and Bifidobacterium, show potential benefits including normalizing intestinal microflora and blocking pathogen invasion.
    • Evidence suggests efficacy in treating diarrhea, managing irritable bowel syndrome and inflammatory bowel disease, and improving lactose intolerance.
    • Potential benefits also include colon cancer prevention, immune modulation, Helicobacter pylori inhibition, and possible enhancement of calcium absorption and cholesterol reduction.

    Conclusions:

    • Adequate viable bacteria count and daily dosage are critical for probiotic efficacy.
    • Probiotics are generally considered safe as food supplements, with a high tolerable intake level.
    • Currently, no disease-prevention or therapeutic claims for probiotics are legally permitted in the United States.