Related Experiment Video
Updated: Aug 15, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Physiologic changes in pregnancy and their impact on critical care
Edward R Yeomans1, Larry C Gilstrap
1Department of Obstetrics and Gynecology, University of Texas Medical School at Houston, Houston, TX, USA.
Critical care for pregnant patients requires understanding major pregnancy-induced physiologic changes. Key cardiovascular and pulmonary system alterations are most crucial for intensive care unit management.
Area of Science:
- Obstetrics and Gynecology
- Critical Care Medicine
- Physiology
Background:
- Pregnancy involves significant maternal physiologic adaptations.
- These adaptations can complicate the management of critically ill patients.
Purpose of the Study:
- To outline key pregnancy-induced physiologic changes relevant to critical care.
- To guide healthcare providers in managing critically ill pregnant patients.
Main Methods:
- Comprehensive literature review of pregnancy-related physiologic alterations.
- Focused abstraction and organization of changes impacting intensive care unit (ICU) patients.
- System-by-system analysis of physiological shifts.
Main Results:
- Multiple organ systems undergo substantial functional changes during pregnancy.
- Cardiovascular system adaptations include increased cardiac output and altered vascular resistance.
- Pulmonary system changes involve increased respiratory rate and altered gas exchange.
Conclusions:
- Understanding pregnancy-induced physiologic changes is vital for effective critical care.
- Cardiovascular and pulmonary system modifications are paramount in intensive care settings.
- These insights are essential for optimizing patient outcomes in critically ill pregnant individuals.
Related Concept Videos
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Pharmacokinetics in Pediatric Patients: Drug Distribution
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Mitral Valve Prolapse III: Nursing Management
Chronic Kidney Disease IV: Nursing Management
