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Updated: Aug 15, 2026

Ultrasound-guided Botulinum Toxin-A Injections: A Method of Treating Sialorrhea
Published on: November 9, 2016
[Treatment of Frey's syndrome using botulinum toxin]
Gregor Bachmann-Harildstad1, Siegfried Wenus, Ole Vik
1Øre-nese-hals-avdelingen, Universitetssykehuset Nord-Norge, 9038 Tromsø. gregor.bachmann@unn.no
Background:
Frey's syndrome, also known as gustatory sweating, has been known for 150 years. However, effective treatment was established only as recently as in 1994, with botulinum toxin used for the treatment of torticollis or other forms of spasticity.
Material And Methods:
We present an overview over Frey's syndrome. Diagnosis with Minors sweating test and treatment with botulinum toxin is presented on the basis of our own experience. Relevant literature was found through Medline.
Results And Interpretation:
Botulinum toxin injected intracutaneously is a safe and effective method for the treatment of Frey's syndrome. The results are convincing and the method is well documented in the literature. So far, no serious side effects have been found.
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