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Updated: Aug 15, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Heart block and empirical therapy after transcatheter closure of perimembranous ventricular septal defect
William C L Yip1, Frank Zimmerman, Ziyad M Hijazi
1Pediatric Cardiology Service, Gleneagles Hospital, Singapore.
Abstract:
Two patients with perimembranous ventricular septal defects (VSDs) and inlet extension have undergone uncomplicated transcatheter device closure using the Amplatzer membranous VSD device. Both patients developed complete heart block 2-4 days from the closure. Both patients responded well to high-dose intravenous therapy with steroids and high-dose oral anti-inflammatory aspirin. Both patients remain in normal sinus rhythm 8 weeks and 10 months, respectively, from the episode.
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