Prominent positive U waves appearing with high-dose intravenous phenylephrine
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Published on: September 13, 2022
David Hefer1, Inna Bukharovich, E John Nasrallah
1Department of Pharmacology, Columbia University, New York, NY 10032, USA. dvh2101@columbia.edu
Abstract:
A 71-year-old woman who had critical cerebral ischemia secondary to a carotid artery occlusion was receiving high-dose intravenous phenylephrine for a trial of hypertensive therapy. While on a maximal dose of phenylephrine she developed prominent positive U waves, which disappeared with the cessation of the drug. The possible underlying electrophysiological mechanisms of this phenomenon are discussed in this paper.
