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[Spanish version of the Memory Impairment Screen (MIS): normative data and discriminant validity]
P Böhm1, J Peña-Casanova, N Gramunt
1Sección de Neurología de la Conducta y Demencias, Institut Municipal d'Assistència Sanitària (IMAS), Hospital del Mar, Barcelona.
Neurologia (Barcelona, Spain)
|October 12, 2005
Summary
The Spanish Memory Impairment Screen (MIS) effectively screens for dementia and Alzheimer's Disease (AD). This validated tool demonstrates high accuracy, making it suitable for early detection in memory clinics.
Area of Science:
- Neuropsychology
- Geriatrics
- Neurology
Context:
- Dementia diagnosis and screening are critical in aging populations.
- The Memory Impairment Screen (MIS) is a cognitive tool used to assess memory function.
- Validation of screening tools in different linguistic and cultural contexts is essential.
Purpose:
- To evaluate the discriminative and normative validity of a Spanish adaptation of the MIS.
- To assess the MIS's utility as a screening instrument for memory problems in primary dementing disorders, particularly Alzheimer's Disease (AD).
- To establish the diagnostic accuracy of the Spanish MIS (S-MIS) in a dementia clinic setting.
Summary:
- A cross-sectional study involving 403 participants (188 with dementia, 119 with AD, 215 controls) evaluated the S-MIS.
- Receiver Operating Characteristic (ROC) curves showed excellent discriminative validity for dementia (0.944) and AD (0.978).
- A cut-off score of <= 4 yielded high sensitivity (0.74 for dementia, 0.86 for AD) and specificity (0.96 for both).
Impact:
- The S-MIS reliably differentiates between cognitively normal and demented individuals.
- The study supports the use of the S-MIS as a first-level screening tool for dementia.
- Findings contribute to the availability of culturally adapted and validated cognitive screening instruments.