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Biologic response of immediately versus delayed loaded implants supporting ill-fitting prostheses: an animal study
Joke Duyck1, Luc Vrielinck, Ivo Lambrichts
1Department of Prosthetic Dentistry, BIOMAT Research Group, Katholieke Universiteit Leuven, Leuven, Belgium. Joke.Duyck@uz.kuleuven.ac.be
Clinical Implant Dentistry and Related Research
|October 13, 2005
Summary
Computer-assisted implant planning can cause prosthesis misfit. This study shows immediately loaded implants adapt to prostheses, minimizing misfit and not compromising osseointegration.
Area of Science:
- Biomaterials science
- Dental implantology
- Surgical planning
Background:
- Computer-assisted preoperative implant planning enables same-day prosthesis fitting.
- A potential drawback is cumulative error leading to prosthesis misfit due to deviations between planned and installed implants.
Purpose of the Study:
- To investigate if prosthesis misfit affects osseointegration in immediately versus delayed loaded implants.
- To determine if newly placed implants can adapt to existing prosthesis fit.
Main Methods:
- Comparison of test (immediately loaded with misfit) and control (delayed loaded with misfit) implants in rabbit tibias.
- Prostheses remained attached for 12 weeks.
- Three-dimensional laser scanning used to measure implant displacement and prosthesis misfit.
Main Results:
- No significant differences in biologic response between test and control implants.
- Test implants showed greater displacement towards prostheses.
- Significant reduction in prosthesis misfit observed in immediately loaded implants.
Conclusions:
- Prosthesis misfit does not inherently cause biologic failure in immediately loaded or osseointegrated implants.
- Immediately loaded implants demonstrate topographic adaptation to prostheses, reducing misfit.

