[Rotavirus diarrhea in a population covered by private health insurance in Córdoba, Argentina]

E Cuestas Montañés1, J Appendino Camacho, M Valle Toselli

  • 1Servicio de Pediatría y Neonatología, Hospital Privado Centro Médico de Córdoba, Centro Formador de la Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Argentina. ecuestas@hospitalprivadosa.com.ar

Insights

Rotavirus is a leading cause of severe childhood diarrhea globally. This study in Argentina found rotavirus was responsible for half of hospitalized cases, with vomiting and dehydration as key indicators.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Gastroenterology

Context:

  • Rotavirus is a primary cause of severe diarrhea in children under five worldwide.
  • Understanding rotavirus incidence and clinical presentation is crucial for public health interventions.

Purpose:

  • To determine the incidence of rotavirus diarrhea in Cordoba, Argentina.
  • To identify clinical signs and symptoms predictive of rotavirus infection.
  • To evaluate the impact of rotavirus on hospital stay duration.

Summary:

  • A case-control study in Argentina (2002-2003) analyzed 73 children, with 33 confirmed rotavirus cases.
  • Rotavirus infections peaked in autumn and early winter.
  • Vomiting (OR 8.40) and dehydration (OR 3.73) were significantly associated with rotavirus, while hospital stay was longer in non-rotavirus cases.

Impact:

  • This research highlights rotavirus's significant contribution to pediatric hospitalizations for diarrhea in the region.
  • Identified key symptoms can aid in early diagnosis and management of rotavirus gastroenteritis.
  • Findings support the need for continued rotavirus surveillance and prevention strategies.
Abstract

Related Concept Videos

Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
Poliomyelitis01:17

Poliomyelitis

Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
Cholera01:25

Cholera

Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...
Drugs for Treatment of Diarrhea-Predominant IBS01:17

Drugs for Treatment of Diarrhea-Predominant IBS

Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
Giardiasis01:12

Giardiasis

Giardiasis is a globally prevalent intestinal infection caused by the protozoan parasite Giardia duodenalis (also known as G. lamblia or G. intestinalis). This flagellated protozoan is the most frequently identified intestinal parasite in the United States and worldwide. Transmission primarily occurs via the fecal-oral route, with infection arising from ingestion of water or food contaminated with cysts. Individuals in low-resource settings, international travelers, outdoor enthusiasts, daycare...