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Updated: Aug 15, 2026

Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus
Published on: January 28, 2019
[Rotavirus diarrhea in a population covered by private health insurance in Córdoba, Argentina]
E Cuestas Montañés1, J Appendino Camacho, M Valle Toselli
1Servicio de Pediatría y Neonatología, Hospital Privado Centro Médico de Córdoba, Centro Formador de la Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Argentina. ecuestas@hospitalprivadosa.com.ar
Insights
Rotavirus is a leading cause of severe childhood diarrhea globally. This study in Argentina found rotavirus was responsible for half of hospitalized cases, with vomiting and dehydration as key indicators.
Area of Science:
- Pediatrics
- Infectious Diseases
- Gastroenterology
Context:
- Rotavirus is a primary cause of severe diarrhea in children under five worldwide.
- Understanding rotavirus incidence and clinical presentation is crucial for public health interventions.
Purpose:
- To determine the incidence of rotavirus diarrhea in Cordoba, Argentina.
- To identify clinical signs and symptoms predictive of rotavirus infection.
- To evaluate the impact of rotavirus on hospital stay duration.
Summary:
- A case-control study in Argentina (2002-2003) analyzed 73 children, with 33 confirmed rotavirus cases.
- Rotavirus infections peaked in autumn and early winter.
- Vomiting (OR 8.40) and dehydration (OR 3.73) were significantly associated with rotavirus, while hospital stay was longer in non-rotavirus cases.
Impact:
- This research highlights rotavirus's significant contribution to pediatric hospitalizations for diarrhea in the region.
- Identified key symptoms can aid in early diagnosis and management of rotavirus gastroenteritis.
- Findings support the need for continued rotavirus surveillance and prevention strategies.
Background:
Rotavirus is the most common cause of severe diarrhea worldwide, especially in children under 5 years of age.
Objectives:
To study the incidence of rotavirus diarrhea in a population in Cordoba, Argentina. To determine signs and symptoms with potential predictive clinical diagnostic value and evaluate how rotavirus diarrhea affects length of hospital stay.
Material And Methods:
A case-control study was performed from April 1, 2002 to March 31, 2003.
Results:
Seventy-three patients were included. There were 33 rotavirus (1) cases and 40 rotavirus (-) controls. The mean age of the rotavirus (1) patients was 16.8 6 2.3 months. There were 14 (42.4 %; 95 % CI: 27.2-59.2) girls and 19 (57.6 %; 95 % CI: 40.8-72.8) boys. The seasonal peak of the disease was observed in the fall (30.3 %; 95 % CI: 17.4-47.3) and at the beginning of the austral winter (39.3 %; 95 % CI: 24.7-56.3). The signs and symptoms associated with the infection were vomiting (OR 8.40; 95 % CI: 2.39-31.33) and dehydration (OR 3.73; 95 % CI: 1.06-13.81). In the 33 rotavirus (1) patients, the mean length of hospital stay was 2.6 days.
Conclusions:
One half of the hospitalized cases were produced by rotavirus. The seasonal peak was observed in autumn and winter (southern hemisphere). Rotavirus (1) patients more frequently presented severe vomiting and dehydration than rotavirus (-) patients, although length of hospital stay and diarrhea were longer in the control group.
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