Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Complications after photodynamic therapy.

Ute E K Schnurrbusch1, Claudia Jochmann, Wilma Einbock

  • 1Department of Ophthalmology, University Eye Hospital, Bern, Switzerland.

Archives of Ophthalmology (Chicago, Ill. : 1960)
|October 13, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Discontinuing Anti-VEGF Therapy in Patients with Neovascular Age-Related Macular Degeneration That Remains Inactive with Treatment at the Maximum Injection Interval.

Clinical ophthalmology (Auckland, N.Z.)·2026
Same author

Monitoring of Geographic Atrophy Progression in Age-Related Macular Degeneration Using Fluorescence Lifetime Imaging Ophthalmoscopy.

Investigative ophthalmology & visual science·2026
Same author

Pathogenesis of diffuse large B cell lymphoma proteogenotypes.

Cancer cell·2026
Same author

vanA-consistent phenotype vancomycin-resistant enterococcal colonization is associated with inferior overall survival in acute myeloid leukemia patients undergoing intensive chemotherapy: a single-center retrospective study.

Infection·2026
Same author

Assessing intergrader variability in incomplete outer retinal atrophy (iRORA) grading.

The British journal of ophthalmology·2026
Same author

The Transdiagnostic Role of Emotion Regulation Difficulties and Repetitive Negative Thinking in Depression, Anxiety, and Their Comorbidity.

Depression and anxiety·2026
Same journal

The economics of the initial preventive physical examination in medicare-reply.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013
Same journal

Modification of silicone oil retention sutures in aphakic eyes with iris loss-reply;.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013
Same journal

December 2011 archives web quiz winner.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013
Same journal

Angle involvement and glaucoma in patients with biopsy-proven iris melanoma: a response-reply.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013
Same journal

About this journal.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013
Same journal

In memoriam: goodwin m. Breinin, MD (1918-2011).

Archives of ophthalmology (Chicago, Ill. : 1960)·2013
See all related articles

Photodynamic therapy (PDT) for age-related macular degeneration and pathologic myopia is generally safe, with uncommon complications. Acute severe visual events occurred in about 3% of patients, a risk outweighed by PDT

Area of Science:

  • Ophthalmology
  • Medical Treatments
  • Retinal Diseases

Background:

  • Age-related macular degeneration (AMD) and pathologic myopia are leading causes of vision loss.
  • Subfoveal choroidal neovascularization (CNV) is a common complication of these conditions.
  • Photodynamic therapy (PDT) with verteporfin is a treatment option for subfoveal CNV.

Purpose of the Study:

  • To evaluate the incidence of complications associated with photodynamic therapy (PDT) using verteporfin.
  • To assess the safety profile of PDT in patients with subfoveal CNV secondary to AMD and pathologic myopia.

Main Methods:

  • Retrospective interventional case series analysis of patient medical records.
  • Inclusion of patients with AMD and pathologic myopia treated with PDT.

Related Experiment Videos

  • Review of complications including systemic adverse events, injection site effects, and ocular adverse events.

    • Main Results:

    • 273 patients (198 AMD, 75 pathologic myopia) with 485 PDT sessions were analyzed.
    • Infusion-related pain (2.2%), dyspnea/flushing (0.7%), body pain/SOB/elevated BP (4.8%), and pruritus (2.2%) were reported.
    • Acute severe visual acuity decrease occurred in 2.9% of patients within 7 days of treatment.

    Conclusions:

    • Complications from PDT are uncommon in patients with AMD and pathologic myopia.
    • Acute severe visual events are a potential complication, occurring in approximately 3% of patients.
    • The benefits of PDT for visual function likely outweigh the risks in most patients.