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Oligodendroglioma metastatic to bone marrow
Firas Al-Ali1, Aaron J Hendon, Marcia K Liepman
1Neurointerventional and Diagnostic Services, Borgess Medical Center, Kalamazoo, MI 49048, USA.
AJNR. American Journal of Neuroradiology
|October 13, 2005
Summary
Oligodendroglioma can metastasize to bone years after resection, causing pancytopenia. This rare bone metastasis presentation, though extensive, showed no vertebral compression on MRI.
Area of Science:
- Neuro-oncology
- Skeletal Metastasis Research
Background:
- Oligodendroglioma is a primary brain tumor.
- Extraneural metastases from oligodendroglioma are rare.
Observation:
- A patient presented with pancytopenia and fever 10 years post-resection of oligodendroglioma.
- Literature review identified 30 extraneural metastases, 19 in bone.
Findings:
- Bone metastases exhibited characteristic MRI signal intensities (T2 high, T1 low) and enhancement.
- Despite extensive disease, MRI revealed no vertebral necrosis or compression.
Implications:
- Highlights the potential for late skeletal metastasis in oligodendroglioma.
- Suggests specific MRI characteristics for identifying bone metastases.
- Underscores the importance of considering extraneural sites in long-term follow-up.