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[Blood pressure control in hypertensive patients with stable coronary heart disease]
B Chamontin1, J Beaune, J P Cambou
1Service de médecine interne, HTA, CHU Rangueil, Toulouse.
Insights
Systolic blood pressure (SBP) control remains a challenge for most hypertensive patients with stable coronary heart disease (CHD). This French study found that 60% of patients did not meet SBP goals, indicating a need for improved combination therapy.
Area of Science:
- Cardiology
- Hypertension Management
- General Practice Research
Context:
- Stable coronary heart disease (CHD) patients often have co-existing hypertension.
- Effective blood pressure control is crucial for secondary prevention in CHD.
- General practice settings play a key role in managing chronic conditions like hypertension and CHD.
Purpose:
- To evaluate the control of systolic blood pressure (SBP) in hypertensive patients with stable coronary heart disease (CHD) within French general practice.
- To identify the proportion of patients achieving target SBP levels (<140/90 mmHg).
Summary:
- A 2003 survey (LHYCORNE) included 595 hypertensive patients with documented CHD from 206 French general practitioners.
- Mean SBP was 140.7 mmHg, with only 40% of patients achieving controlled SBP (<140 mmHg).
- Control rates were lower in patients with angina pectoris (38%) compared to myocardial infarction (47%).
Impact:
- Findings indicate suboptimal SBP control in a majority (60%) of hypertensive patients with stable CHD.
- Suggests a significant opportunity to optimize antihypertensive treatment strategies, including combination therapy.
- Highlights the need for adherence to evidence-based medicine guidelines for improved cardiovascular outcomes.
Objective:
To evaluate systolic blood pressure (SBP) control in hypertensive patients with a stable coronary heart disease (CHD) in general practice in France.
Methods:
A survey was conducted in a sample of 206 general practitionners (GP) representative of the French medical population, in 2003 [LHYCORNE survey]. Each GP had to include 3 hypertensive patients, >18 years old, BP > or = 140/90 mmHg and/or treated for hypertension, and with evidence of CHD documented by myocardial infarction (MI) or angina pectoris (AP) [diagnosis previously established by a cardiologist]. Three office BP measurements were performed, the last two recorded. BP levels were considered as controlled by treatement if they were < 140/90 mmHg.
Results:
595 patients were included, 75% men mean age 66 years, 25% women mean age 73 years. All patients had a CHD: MI 46%, AP 54%; 533 (90%) had more than 2 cardiovascular risk factors: hyperlipidemia (411; 69%), smokers (375; 63%), diabetes (158; 27%). Mean BP was 140.7 +/- 14/80.8 +/- 9.7 mmHg; 553 (93%) of these hypertensive patients were treated, and 239 (40%) were considered as having a controlled SBP at the treshold of 140 mmHg: 47% in patients with previous MI and 38% with AP (p < 0.001). Diastolic BP (DBP) was <90 mmHg in 480 (81%) and pulse pressure was >65 mmHg in 202 (34%); 313 (53%) patients received a combination of three drugs or more; 354 (60%) had a beta-blocker, 260 (44%) a calcium channel blocker, 237 (40%) an ACE inhibitor, 287 (48%) other antihypertensive drugs (246 diuretics, 41%); 502 (84%) received antiplatelet therapy, 403 (68%) statins.
Conclusion:
This survey shows that systolic BP is not at goal in 6/10 hypertensive patients with stable CHD suggesting there is a place for a more effective combination therapy according to evidence-based medicine.
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