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A new flavanone from Dryopteris sublaeta.

Wei-sheng Feng1, Xin-wei Cao, Xiao-ke Zheng

  • 1Henan College of Traditional Chinese Medicine, Zhengzhou 450008, China. fwsh@hactcm.edu.cn

Yao Xue Xue Bao = Acta Pharmaceutica Sinica
|October 14, 2005
PubMed
Summary

This study isolated four chemical compounds from Dryopteris sublaeta, including a novel flavanone and three other compounds new to the Dryopteris genus.

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Area of Science:

  • Phytochemistry
  • Natural Product Chemistry
  • Pharmacognosy

Background:

  • Dryopteris species are known for their diverse chemical profiles.
  • Understanding the chemical constituents of Dryopteris sublaeta is crucial for potential applications.

Purpose of the Study:

  • To investigate and identify the chemical constituents present in Dryopteris sublaeta.
  • To characterize novel compounds and those previously unisolated from this species.

Main Methods:

  • Extraction of fresh Dryopteris sublaeta using boiling water.
  • Fractionation of the extract using ether, ethyl acetate, and n-butanol.
  • Purification and identification of compounds via silica gel column chromatography and spectral data analysis.

Main Results:

  • Four compounds were successfully isolated and identified.
  • Compound 1: 2(S)-5,7,3'-trihydroxy-6,8-dimethyl-5'-methoxyflavanone (a new compound).
  • Compounds 2, 3, and 4: matteucinol, desmethoxymatteucinol, and 5,7,2'-trihydroxy-6,8-dimethylflavanone, respectively, isolated for the first time from Dryopteris.

Conclusions:

  • A new flavanone derivative was discovered in Dryopteris sublaeta.
  • The study expands the known phytochemical diversity of the Dryopteris genus.

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