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Updated: Aug 15, 2026

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
Published on: August 14, 2019
A new flavanone from Dryopteris sublaeta
Wei-sheng Feng1, Xin-wei Cao, Xiao-ke Zheng
1Henan College of Traditional Chinese Medicine, Zhengzhou 450008, China. fwsh@hactcm.edu.cn
Aim:
To study the chemical constituents of Dryopteris sublaeta Ching et Hsu.
Methods:
Fresh plant of Dryopteris sublaeta Ching et Hsu was extracted twice with boiling water, the extract was concentrated to small volume under reduced pressure at 50 degrees C. The concentrated material was partitioned with ether, ethyl acetate, and n-butanol. The fraction of ether extract was chromatographed over silica gel column. The compounds were identified on the basis of their physiochemical and spectral data.
Results:
Four compounds were obtained and identified as 2 (S)-5, 7, 3'-trihydroxy-6, 8-dimethyl-5'-methoxyflavanone (1), matteucinol (2), desmethoxymatteucinol (3) and 5, 7, 2'-trihydroxy-6, 8-dimethylflavanone (4).
Conclusion:
Compound 1 is a new one, the others were isolated from Dryopteris for the first time.
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