Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

HL7 Clinical Document Architecture, Release 2.

Robert H Dolin1, Liora Alschuler, Sandy Boyer

  • 1Kaiser Permanente, Pasadena, CA, USA. robert.h.dolin@kp.org

Journal of the American Medical Informatics Association : JAMIA
|October 14, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The GA4GH Categorical Variation Representation Specification: A Unified Computational Framework for Reasoning over Genomic Variant Categories.

bioRxiv : the preprint server for biology·2026
Same author

Assessment of the adequacy of the Fast Healthcare Interoperability Resources (FHIR) Genomics standard for the representation of somatic testing reports.

JAMIA open·2026
Same author

Genetic data normalization for genomic medicine: a Fast Healthcare Interoperability Resources Genomics reference implementation.

Journal of the American Medical Informatics Association : JAMIA·2025
Same author

The National Healthcare Safety Network's digital quality measures: CDC's automated measures for surveillance of patient safety.

Journal of the American Medical Informatics Association : JAMIA·2024
Same author

PillHarmonics: An Orchestrated Pharmacogenetics Medication Clinical Decision Support Service.

Applied clinical informatics·2024
Same author

Automated HL7v2 LRI informatics framework for streamlining genomics-EHR data integration.

Journal of pathology informatics·2023
Same journal

Reporting follow-up budgets for diagnostic and predictive AI.

Journal of the American Medical Informatics Association : JAMIA·2026
Same journal

Digital divide in clinical and operational artificial intelligence adoption and implementation stages: US hospital diffusion patterns and AI deserts.

Journal of the American Medical Informatics Association : JAMIA·2026
Same journal

Extending the fundamental theorem of biomedical informatics: a proposal and illustrative examples.

Journal of the American Medical Informatics Association : JAMIA·2026
Same journal

Human factors methods for designing safe health information technology: what do the experts think?

Journal of the American Medical Informatics Association : JAMIA·2026
Same journal

Equity-by-design for socially assistive robots as digital health tools.

Journal of the American Medical Informatics Association : JAMIA·2026
Same journal

Orchestrator multi-agent clinical decision support system for secondary headache diagnosis in primary care.

Journal of the American Medical Informatics Association : JAMIA·2026
See all related articles

Clinical Document Architecture (CDA) Release Two enhances semantic representation for clinical events, building upon CDA Release One. This standard facilitates widespread adoption and incremental interoperability in healthcare data exchange.

Area of Science:

  • Health Informatics
  • Computer Science
  • Medical Standards

Background:

  • Clinical Document Architecture (CDA) Release One (R1) was established as an ANSI-approved HL7 Standard in 2000.
  • CDA R1 was the initial specification derived from the Health Level 7 (HL7) Reference Information Model (RIM).

Purpose of the Study:

  • To detail the evolution of the CDA standard, focusing on CDA Release Two (R2).
  • To emphasize advancements in the semantic representation of clinical events within CDA R2.
  • To explore how CDA R2 facilitates widespread adoption and semantic interoperability.

Main Methods:

  • Analysis of the CDA R2 specification.
  • Comparison of CDA R2 features with CDA R1.
  • Examination of CDA R2's structure, semantics, and encoding (XML).

Related Experiment Videos

Main Results:

  • CDA R2 significantly enhances the semantic representation of clinical statements, enabling computer interpretation and action.
  • The standard supports formal representation of observations, medication administrations, and adverse events.
  • CDA R2 offers flexible adoption pathways, including wrapping non-XML documents or using narrative content.

Conclusions:

  • CDA R2 represents a significant advancement in clinical document exchange standards.
  • The standard balances rich semantic capabilities with a low barrier to adoption.
  • CDA R2 promotes incremental semantic interoperability for healthcare data.