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Tracheal, bronchial, and pulmonary papillomatosis in children

Iouri L Soldatski1, Elena K Onufrieva, Andrei M Steklov

  • 1Department of Otorhinolaryngology, IM Sechenov Moscow Medical Academy, Russia. ysoldatsky@aport.ru

The Laryngoscope
|October 14, 2005
PubMed

Insights

Recurrent respiratory papillomatosis can spread to the lower airways, especially after tracheotomy in children. Lower airway papillomatosis has a more aggressive clinical course and poorer treatment outcomes compared to laryngeal papillomatosis.

Area of Science:

  • Pediatric Otolaryngology
  • Respiratory Medicine
  • Oncology

Background:

  • Recurrent respiratory papillomatosis (RRP) is a rare disease characterized by the growth of papillomas in the respiratory tract.
  • Laryngeal papillomatosis is the most common form, but extension to the lower airways can occur.

Purpose of the Study:

  • To compare the clinical course of tracheal, bronchial, and pulmonary papillomatosis with laryngeal papillomatosis in children.
  • To identify risk factors and outcomes associated with lower airway RRP.

Main Methods:

  • Retrospective review of 448 children with RRP treated between 1988 and 2003.
  • Analysis of patient demographics, surgical history, disease spread, and clinical course.

Main Results:

  • Lower airway RRP occurred in 8.9% of cases, with pulmonary involvement in 20% of those.
  • Tracheotomy was the primary cause of lower airway spread (92.5%).
  • Lower airway RRP demonstrated a more aggressive course and lower treatment efficacy.

Conclusions:

  • Children with laryngeal papillomatosis and a history of tracheotomy require vigilant endoscopic and imaging surveillance for potential lower airway involvement.
  • The prognosis for pulmonary papillomatosis is serious, necessitating early detection and management.
Abstract

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