[Mitotic activity in serous adenocarcinoma of the uterine body]

A comparative study of uterine serous (36) and endometrial (32) adenocarcinoma was undertaken. The former pathology revealed a higher mitotic index (18.2%) than the latter (11.4%) (p < 0.01). Predominance of metaphases among the variety of mitotic phases as well as high metaphase-prophase index (73.6% and 69.2% in serous and endometrial adenocarcinoma, respectively) were typical of malignant tumors in general. The share of patholological mitoses in serous adenocarcinomas was 1.6 times (61.8%) that in endometrial adenocarcinomas. Moreover, serous adenocarcinomas showed a wide range of pathological mitoses which were often responsible for aneuploidy development. The above differences in uterine serous and endometrial adenocarcinoma were in full conformity with the well known aggressive nature of the former pathology and may be used as an additional criterion of differential diagnosis.