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Related Experiment Videos

Virtopsy: postmortem minimally invasive angiography using cross section techniques--implementation and preliminary

Christian Jackowski1, Martin Sonnenschein, Michael J Thali

  • 1Institute of Forensic Medicine, University of Bern, Bühlstr. 20, 3012 Bern, Switzerland. christian.jackowski@irm.unibe.ch

Journal of Forensic Sciences
|October 18, 2005
PubMed
Summary

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Minimally invasive CT angiography offers excellent visualization of the arterial system in postmortem investigations. This technique aids in detecting vascular pathologies like calcification and stenosis.

Area of Science:

  • Forensic Medicine
  • Radiology
  • Vascular Imaging

Background:

  • Postmortem Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) are increasingly utilized.
  • There is a growing need for noninvasive or minimally invasive autopsy techniques.
  • Vascular cross-section diagnostics require advanced angiography methods.

Purpose of the Study:

  • To develop and evaluate a minimally invasive CT angiography technique for postmortem vascular investigation.
  • To assess the applicability of contrast agents for postmortem CT and MRI.
  • To visualize the human arterial system and detect vascular pathologies noninvasively.

Main Methods:

  • Preliminary experiments used an ex-vivo porcine coronary model to test contrast agents for CT and MRI.

Related Experiment Videos

  • Minimally invasive Multi-Slice CT (MSCT) angiography was performed on three human corpses.
  • A radiopaque contrast agent (meglumine-ioxithalamate) was injected via the femoral artery into the aortic arch.

    • Main Results:

    • MSCT angiography provided excellent anatomic visualization of the human arterial system, including intracranial and coronary arteries.
    • Vascular pathologies such as calcification, stenosis, and injury were successfully detected.
    • The technique demonstrated high efficacy in postmortem vascular imaging.

    Conclusions:

    • Minimally invasive CT angiography is a valuable tool for postmortem vascular investigation.
    • The technique allows for detailed visualization and detection of pathologies in the arterial system.
    • Limitations include advanced decay and major vessel injury cases.