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Related Experiment Videos

Lidocaine suppositories for prostate biopsy.

Klaus G Fink1, Andrea Gnad, Phillip Meissner

  • 1Urology, Salzburger Landeskliniken, Paracelsus Private Medical University, Salzburg, Austria. k.g.fink@salk.at

BJU International
|October 18, 2005
PubMed
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Lidocaine suppositories significantly reduce pain during transrectal prostate biopsy compared to gel. Applied 1-2 hours prior, suppositories offer a cheaper, more effective pain management option for this common procedure.

Area of Science:

  • Urology
  • Anesthesiology
  • Pharmacology

Background:

  • Transrectal prostate biopsy is a common urological procedure.
  • Pain management during transrectal prostate biopsy is crucial for patient comfort.
  • Current methods like lidocaine gel have variable efficacy.

Purpose of the Study:

  • To evaluate the efficacy of transrectal lidocaine suppositories for pain reduction during transrectal prostate biopsy.
  • To compare the effectiveness of lidocaine suppositories with traditional lidocaine gel.
  • To assess the cost-effectiveness of lidocaine suppositories.

Main Methods:

  • A randomized prospective study involving 100 patients.
  • Patients received either placebo, lidocaine gel (10 min pre-biopsy), or lidocaine suppositories (1 or 2 hours pre-biopsy).

Related Experiment Videos

  • Pain was measured using a visual linear analog scale (0-100).

    • Main Results:

    • Lidocaine suppositories applied 2 hours prior resulted in the lowest mean pain score (21.2).
    • Patients receiving lidocaine suppositories reported significantly less pain than placebo or lidocaine gel.
    • Lidocaine suppositories were more effective than gel, with 2-hour application showing superior pain reduction (P=0.002).

    Conclusions:

    • Transrectal lidocaine suppositories are a significantly more effective method for reducing pain during prostate biopsy than lidocaine gel.
    • Lidocaine suppositories offer a cost-effective (0.63 euros/application) and easy-to-use alternative.
    • The study recommends lidocaine suppositories for routine use in prostate biopsy pain management.