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Validation of a HPLC method for the determination of bendazac and its main metabolite 5-hydroxybendazac in human
B Catanese1, M Panei, R Picollo
1Istituto Ricerca Francesco Angelini S.p.A., Rome, Italy.
Bollettino Chimico Farmaceutico
|January 1, 1992
Abstract:
The purpose of this study was to validate an analytical method for the determination of bendazac and its main metabolite 5-hydroxybendazac in human plasma. The results obtained indicate that the method is reproducible, accurate, precise, sensitive and specific for the measurement of bendazac and 5-hydroxybendazac in the human plasma. Therefore it can be considered suitable for experimental purposes, routine application for drug monitoring and regulatory requirements.