Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Time-lapse analysis of retinal differentiation.

Lucia Poggi1, Flavio R Zolessi, William A Harris

  • 1Department of Anatomy, Downing St, Cambridge University, Cambridge CB2 3DY, UK.

Current Opinion in Cell Biology
|October 18, 2005
PubMed
Summary

New vital markers and time-lapse microscopy reveal retinal development insights. This technology clarifies cell fate, progenitor migration, and retinal ganglion cell axon guidance.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mitochondrial preservation underlies the antioxidant activity of nanoceria particles in light-induced retinal degeneration.

Nanomedicine : nanotechnology, biology, and medicine·2026
Same author

Priming neuronal regeneration: early adaptive mechanisms in zebrafish CNS injury.

Frontiers in molecular neuroscience·2026
Same author

Oxidative Stress Signaling and Regenerative Responses in a Larval Zebrafish Model of Retinal Light Damage.

Antioxidants (Basel, Switzerland)·2026
Same author

Spectral Phasor Analysis for Hyperspectral Imaging to Elucidate Acridine Orange Photophysics in Cells.

Microscopy research and technique·2026
Same author

Mechanical conditions preventing live cell extrusion during primary neurulation in amniotes.

Cells & development·2025
Same author

Multifaceted disruption of AMPA receptor signaling by <i>CACNG8</i> variants: Integrated evidence from human genetics and molecular simulation.

Computational and structural biotechnology journal·2025

Area of Science:

  • Developmental biology
  • Neuroscience
  • Ophthalmology

Background:

  • Understanding retinal development is crucial for treating visual disorders.
  • Traditional methods limited real-time observation of dynamic cellular processes.

Purpose of the Study:

  • To leverage advanced microscopy and vital markers for observing retinal development in vivo.
  • To elucidate key developmental events including cell division, migration, and axon pathfinding.

Main Methods:

  • Utilized novel vital markers for cellular identification.
  • Employed time-lapse video microscopy to capture dynamic developmental processes.
  • Focused on retinal development from progenitor cells to mature neuronal connections.

Main Results:

Related Experiment Videos

  • Established correlations between cell division patterns and cell fate determination.
  • Documented the precise migration pathways of post-mitotic progenitors to their designated retinal layers.
  • Observed the navigation mechanisms of retinal ganglion cell axons toward midbrain targets.

Conclusions:

  • Advanced imaging techniques provide unprecedented insights into retinal development.
  • These findings enhance our understanding of neural circuit formation in the visual system.
  • This approach holds potential for future research in developmental neuroscience and ophthalmology.