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Updated: Aug 15, 2026
10:07
Investigation of Macrophage Polarization Using Bone Marrow Derived Macrophages
Published on: June 23, 2013
Macrophage polarization comes of age
Alberto Mantovani1, Antonio Sica, Massimo Locati
1Istituto Clinico Humanitas, and Institute of General Pathology, University of Milan, Milan, Italy.
Immunity
|October 18, 2005
Abstract:
Functional polarization of macrophages into M1 or M2 cells is an operationally useful, simplified conceptual framework describing the plasticity of mononuclear phagocytes. Genetic approaches have begun to shed new light on mechanisms underlying macrophage polarization and on the actual in vivo significance of polarized M2 cells ( [this issue of Immunity]).
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