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Metastatic choroidal tumors in Taiwan: an 11-year experience
Tsung-Jen Wang1, Chung-May Yang, Tzyy-Chang Ho
1Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.
Purpose:
To report the clinical features, the primary sites, and overall prognosis of choroidal metastasis.
Design:
Observational case series.
Methods:
Included were all cases of choroidal metastases evaluated at National Taiwan University Hospital over an 11-year period. Patients with blood or lymphoproliferative diseases were excluded. Clinical features were correlated with disease entity and prognosis.
Results:
A total of 36 patients with choroidal metastases were identified. The mean age was 53.9 +/- 12.8 years. The mean follow-up period was 5.1 +/- 4.2 months. The primary sites of tumors were lung in 18 (50%), breast in eight (22.2%), gastrointestinal tract in three (8.3%), pancreas in two (5.6%), ovary in two (5.6%), kidney in one (2.8%), liver in one (2.8%), and unknown in one (2.8%). Twenty-two patients (61%) died during follow-up. Mean life span after diagnosis was 4.3 months in these 22 patients.
Conclusions:
Lung and breast cancers represent more than two thirds of primary tumor sites. Choroidal metastases may indicate terminal status of the underlying malignancy and short survival time.
