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Endogenous Phialemonium curvatum endophthalmitis.

Shiri Zayit-Soudry1, Meira Neudorfer, Adiel Barak

  • 1Department of Ophthalmology, Tel-Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel. shirizayit@hotmail.com

American Journal of Ophthalmology
|October 18, 2005
PubMed
Summary
This summary is machine-generated.

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This case report details a rare instance of bilateral endogenous endophthalmitis caused by Phialemonium curvatum (P. curvatum) infection, stemming from intrapenile injections for erectile dysfunction.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Mycology

Background:

  • Endogenous endophthalmitis is a severe intraocular infection.
  • Intrapenile injections for erectile dysfunction can introduce pathogens into the bloodstream.

Observation:

  • A 71-year-old male presented with bilateral decreased vision and was diagnosed with P. curvatum endophthalmitis.
  • P. curvatum was identified in vitreous cultures.
  • The patient had a history of P. curvatum endocarditis.

Findings:

  • Treatment involved bilateral vitrectomy and systemic/intraocular antifungals.
  • Despite treatment, visual acuity remained poor (hand movement).
  • The ophthalmic condition did not improve significantly post-surgery.

Related Experiment Videos

Implications:

  • Phialemonium curvatum can cause severe endogenous endophthalmitis.
  • This represents a potentially novel cause of ocular infection.
  • Early diagnosis and aggressive treatment are crucial, though outcomes can be poor.