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Metastasis to appendix from lung adenocarcinoma
Kunihiko Miyazaki1, Hiroaki Satoh, Kiyohisa Sekizawa
1Division of Respiratory Medicine, Institute of Clinical Medicine, University of Tsukuba, Tsukuba-city, Ibaraki, Japan.
International Journal of Gastrointestinal Cancer
|October 18, 2005
Summary
Appendiceal metastasis from lung adenocarcinoma is rare. This case report details a patient with a history of lung cancer who developed an appendiceal tumor, confirmed to be metastatic from the lung primary.
Area of Science:
- Gastroenterology
- Oncology
- Surgical Pathology
Background:
- Appendiceal metastasis from a distant primary malignancy is an uncommon clinical presentation.
- Pancreatic adenocarcinoma has been reported as a primary source of appendiceal metastases.
- This report presents a rare case of appendiceal metastasis originating from lung adenocarcinoma.
Observation:
- A 64-year-old male with a history of locally advanced lung adenocarcinoma presented with abdominal pain and fever.
- Abdominal CT revealed a pelvic mass, later identified as an appendiceal tumor.
- Histological examination confirmed the appendiceal tumor was morphologically similar to the patient's primary lung cancer.
Findings:
- The appendiceal tumor infiltrated the submucosa, muscularis, and serosa, with intact mucosa.
- The tumor was surgically excised along with an ileocecal resection.
- The patient experienced an uneventful postoperative recovery but ultimately succumbed to lung cancer 12 months later.
Implications:
- This case highlights the importance of considering extradigestive primary tumors in the differential diagnosis of appendiceal masses.
- Accurate diagnosis of appendiceal tumors is crucial for appropriate patient management and prognosis.
- Further research into the mechanisms and clinical implications of rare metastatic patterns is warranted.