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Intraocular pressure measurement over amniotic membrane patch in human subjects
Akihiro Hashizume1, Tomohiko Usui, Seiichi Yokoo
1Department of Ophthalmology, Faculty of Medicine, University of Tokyo, Japan.
Cornea
|October 18, 2005
Summary
The Tono-Pen XL accurately measures intraocular pressure (IOP) even when a human amniotic membrane is present. This finding supports its use for IOP monitoring in patients with ocular surface patching.
Area of Science:
- Ophthalmology
- Biomedical Engineering
Background:
- Accurate intraocular pressure (IOP) measurement is crucial for diagnosing and managing glaucoma.
- Amniotic membrane patching is a common procedure for ocular surface reconstruction and healing.
- The presence of a membrane may potentially affect IOP readings.
Purpose of the Study:
- To evaluate the accuracy of Tono-Pen tonometry for measuring IOP over a human amniotic membrane.
- To determine if amniotic membrane patching significantly alters IOP measurements obtained with the Tono-Pen XL.
Main Methods:
- Intraocular pressure (IOP) was measured in 28 normal eyes using a handy applanation tonometer and the Tono-Pen XL.
- A single layer of human amniotic membrane (approx. 50 microm) was applied to the corneal surface.
- IOP was re-measured using the Tono-Pen XL with the amniotic membrane in place.
Main Results:
- Mean IOP without membrane: 14.3 +/- 2.1 mm Hg (handy applanation) and 14.3 +/- 2.4 mm Hg (Tono-Pen XL).
- Mean IOP with amniotic membrane: 14.7 +/- 2.6 mm Hg (Tono-Pen XL).
- No significant overestimation of IOP was observed with the amniotic membrane; bias was minimal (-0.40 to -0.18 mm Hg).
Conclusions:
- The Tono-Pen XL demonstrates high accuracy for IOP measurement in the presence of amniotic membrane patching.
- The device is reliable and useful for monitoring IOP in patients undergoing ocular surface treatments with amniotic membranes.